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Celecoxib alleviates AKT/c-Met-triggered rapid hepatocarcinogenesis by suppressing a novel COX-2/AKT/FASN cascade

van der Esch, M

Accumulation of these compounds can result in oxidative stress, which occurs when the generation of free radicals in the body exceeds the bodys ability to neutralize and eliminate them

We utilized Superscript III reverse transcriptase enzyme (Invitrogen) with random hexamer primers and 3 g of RNA from each sample to produce cDNA according to the manufacturers protocol

H 2 O 2 and chloride ions (Cl ) are further metabolized by myeloperoxidase to hypochlorous acid (HOCL), thereby contributing to chlorinated stress

79 McBurneyM